Related Experiment Video
Updated: Apr 7, 2026

08:48
Optical Recording of Suprathreshold Neural Activity with Single-cell and Single-spike Resolution
Published on: September 5, 2012
12.5K
Note: Using fast digitizer acquisition and flexible resolution to enhance noise cancellation for high performance
A Rimshaw1, C Grieco1, J B Asbury1
1Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.
The Review of Scientific Instruments
|July 3, 2015
Abstract:
We demonstrate a nanosecond transient absorbance spectrometer that utilizes flexible resolution and rapid data acquisition triggering modes. The instrument features signal-to-noise (S/N) levels enhanced by an order of magnitude especially within the first 100 ns. The primary gain in S/N comes from our sequential subtraction method, which requires a fast digitizer trigger rearm time to detect every laser trigger event.

