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Updated: Oct 12, 2026

Body Composition and Metabolic Caging Analysis in High Fat Fed Mice
Published on: May 24, 2018
Short and long term effects of a very low calorie diet on resting metabolic rate and body composition
G Vansant1, L Van Gaal, K Van Acker
1Department of Endocrinology, Metabolism and Clinical Nutrition, University of Antwerp, Belgium.
Abstract:
Short and long term effects of a protein sparing modified fast (PSMF) diet on resting metabolic rate (RMR) and body composition were investigated. During a period of 6 months on diet, RMR decreased significantly, both in absolute value and after correction for fat-free mass (FFM). Short term evaluation with this type of diet showed no decrease in RMR. The results from this study indicate that the fall in RMR associated with a PSMF diet (weight loss) is not due to an acute adaptation to the lower energy intake. Changes in FFM are important in the change in RMR, but other factors have to be involved.
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