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Correlation of Cu(PTSM) localization with regional blood flow in the heart and kidney
A J Barnhart1, W D Voorhees, M A Green
1School of Pharmacy, Purdue University, West Lafayette, IN 47907.
Abstract:
In a dog model of myocardial ischemia, i.v. injection of [67Cu]Cu(PTSM) leads to an excellent linear correlation for both the heart and kidney between regional tissue radiocopper concentration and regional blood flow measured by radioactive micropheres. The 62Cu-labeled complex may serve as a generator-produced position-emitting perfusion tracer for these organs.