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Updated: Apr 7, 2026

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections
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Periprosthetic joint infection.

Bhaveen H Kapadia1, Richard A Berg2, Jacqueline A Daley3

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Summary
This summary is machine-generated.

Periprosthetic joint infections are a serious complication after joint replacement surgery, increasing revision rates. Enhanced prevention, diagnosis, and treatment are crucial for better patient outcomes.

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Area of Science:

  • Orthopaedic surgery
  • Infectious diseases

Background:

  • Periprosthetic joint infections (PJIs) are a significant complication following arthroplasty, leading to substantial patient morbidity.
  • PJIs account for over 25% of revision surgeries, with increasing incidence due to rising comorbidities like obesity and diabetes.

Purpose of the Study:

  • To review risk factors, preventive strategies, diagnostic methods, clinical features, and treatment options for PJIs.
  • To highlight best practices and identify research needs based on an international consensus meeting.

Main Methods:

  • Comprehensive review of current literature on periprosthetic joint infections.
  • Analysis of risk factors, prevention (preoperative, intraoperative, postoperative), diagnosis, and treatment strategies.
  • Incorporation of findings from an international consensus meeting on PJIs.

Main Results:

  • Enhanced preventive measures (e.g., glycaemic control, skin decontamination, ultraclean environments) are being implemented.
  • Refined indications for surgical management and postoperative care (e.g., anticoagulation, wound dressings) are noted.
  • An international consensus identified best practices and areas for future research.

Conclusions:

  • Periprosthetic joint infections pose a growing challenge in arthroplasty, necessitating improved management strategies.
  • Orthopaedic care can significantly benefit from advancements in preventive, diagnostic, and therapeutic approaches for PJIs.
  • Further research and adherence to best practices are essential to combat PJIs effectively.