Related Experiment Video
Updated: Apr 7, 2026

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling
Published on: April 7, 2015
Splenic abscess associated with infective endocarditis; Case series
Abdelfatah Elasfar1, Abdulaziz AlBaradai2, Ziyad AlHarfi2
1Prince Salman Heart Center, King Fahd Medical City, Riyadh, Saudi Arabia ; Faculty of Medicine, Tanta University, Egypt.
Insights
Splenic abscess, a rare infective endocarditis complication, requires prompt diagnosis and treatment. Early splenectomy combined with antibiotics and valve surgery offers a potentially life-saving approach for patients.
Area of Science:
- Infectious Diseases
- Cardiology
- Surgical Management
Background:
- Splenic abscess is a rare but serious complication of infective endocarditis.
- Delayed diagnosis and treatment can lead to fatal outcomes.
Purpose of the Study:
- To present case reports on the management of splenic abscesses in patients with infective endocarditis.
- To evaluate the effectiveness of splenectomy in conjunction with other treatments.
Main Methods:
- Case series of three patients diagnosed with splenic abscess secondary to infective endocarditis.
- Diagnosis confirmed via abdominal computed tomography (CT) or magnetic resonance imaging (MRI).
- Management involved splenectomy (pre- or post-cardiac surgery) and antibiotic therapy.
Main Results:
- All three patients successfully recovered after treatment.
- Splenectomy was performed either before or after valve replacement surgery.
- Outpatient follow-up confirmed satisfactory patient outcomes.
Conclusions:
- Immediate splenectomy, appropriate antibiotics, and valve replacement surgery are crucial for managing splenic abscess in infective endocarditis.
- A multidisciplinary team approach is recommended for optimal patient outcomes.
- This combined strategy may represent the treatment of choice for this clinical scenario.
Abstract:
Splenic abscess is a well-described but rare complication of infective endocarditis. Rapid diagnosis and treatment are essential as its course can be fatal. We present three case reports that describe the management of splenic abscesses in patients initially diagnosed with infective endocarditis. In all cases, the diagnosis was based on the findings of abdominal computed tomography (CT) scan or magnetic resonance imaging (MRI). In two of the cases, splenectomy was performed before valve surgery; while in the third case, the spleen was removed after cardiac surgery. All three patients recovered fully, with satisfactory follow-up as outpatients. Immediate splenectomy, combined with appropriate antibiotics and valve replacement surgery alongside multi-disciplinary team work could be the treatment of choice in this clinical scenario.
More Related Videos
Related Concept Videos
Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis I: Introduction
Endocarditis IV: Nursing Management
Endocarditis III: Medical Management
Rheumatic Heart Disease I: Introduction
Pericarditis II: Clinical Features and Diagnostic Tests

