Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bone Cells and Tissue01:30

Bone Cells and Tissue

12.6K
Bones contain a relatively small number of cells entrenched in a matrix of organic and inorganic components. Although bone cells compose only a small amount of the bone volume, they are crucial to its function. Four types of cells are found within the bone tissue— osteoblasts, osteocytes, osteogenic cells, and osteoclasts.
Osteoblasts and Osteocytes
The osteoblast is the bone cell responsible for forming new bone tissue. It is found in the growing portions of bone, including the...
12.6K
Bone Remodeling01:40

Bone Remodeling

41.1K
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
41.1K
Bone as Supporting Connective Tissue01:23

Bone as Supporting Connective Tissue

8.1K
Bone tissue forms the internal skeleton of vertebrate animals, providing structure to the body.
Bone Matrix
Bone, or osseous tissue, is a connective tissue that has a large amount of two different types of matrix material. The organic matrix is similar to the matrix material found in other connective tissues, including some amount of collagen and elastic fibers. This gives strength and flexibility to the tissue. The inorganic matrix consists of mineral salts— mostly calcium salts—...
8.1K
Growth of Cartilage and Bone Tissue01:27

Growth of Cartilage and Bone Tissue

4.9K
Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...
4.9K
Bone Structure01:55

Bone Structure

53.1K
Within the skeletal system, the structure of a bone, or osseous tissue, can be exemplified in a long bone, like the femur, where there are two types of osseous tissue: cortical and cancellous.
53.1K
Bone Formation by Endochondral Ossification01:24

Bone Formation by Endochondral Ossification

14.7K
Bone formation, or ossification, begins around the sixth to seventh week of embryonic development. Most bones develop from a cartilaginous template through the process of endochondral ossification. Cartilage formation begins when clusters of mesenchymal cells differentiate into chondrocytes. These chondrocytes proliferate rapidly and secrete an extracellular matrix that becomes encased in a membrane called the perichondrium. The resulting cartilage model provides a template that resembles the...
14.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Oncologic profile of maxillary odontogenic myxoma: A rare case.

Contemporary clinical dentistry·2013
See all related articles

Related Experiment Video

Updated: Apr 7, 2026

Half-segmental Diaphyseal Bone Defect Model in Rats for Evaluating Bone Substitute Performance in Load-bearing Regions
04:32

Half-segmental Diaphyseal Bone Defect Model in Rats for Evaluating Bone Substitute Performance in Load-bearing Regions

Published on: December 30, 2025

233

Osteoid producing primary lesion at morphologic and biologic interface.

Reena Radhikaprasad Sarkar1

  • 1Department of Oral and Maxillofacial Pathology, National Dental College Derabassi, Mohali, Punjab, India.

Clinical Cases in Mineral and Bone Metabolism : the Official Journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases
|July 3, 2015
PubMed
Summary
This summary is machine-generated.

This study details a rare pediatric fibroosseous gnathic lesion with a benign radiographic appearance but aggressive histopathology. It highlights unusual features within this disease spectrum.

Keywords:
anaplasiafibroosseousneoplasmosteoidosteosarcomapediatric

More Related Videos

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
08:07

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma

Published on: April 12, 2019

7.8K
Author Spotlight: Enhancing Bone Regeneration with Vascularized Artificial Cartilage Integration
06:05

Author Spotlight: Enhancing Bone Regeneration with Vascularized Artificial Cartilage Integration

Published on: July 14, 2023

1.7K

Related Experiment Videos

Last Updated: Apr 7, 2026

Half-segmental Diaphyseal Bone Defect Model in Rats for Evaluating Bone Substitute Performance in Load-bearing Regions
04:32

Half-segmental Diaphyseal Bone Defect Model in Rats for Evaluating Bone Substitute Performance in Load-bearing Regions

Published on: December 30, 2025

233
Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
08:07

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma

Published on: April 12, 2019

7.8K
Author Spotlight: Enhancing Bone Regeneration with Vascularized Artificial Cartilage Integration
06:05

Author Spotlight: Enhancing Bone Regeneration with Vascularized Artificial Cartilage Integration

Published on: July 14, 2023

1.7K

Area of Science:

  • Oral pathology
  • Pediatric oncology
  • Skeletal biology

Background:

  • Fibroosseous gnathic lesions represent a diverse group of conditions affecting the jawbones.
  • Accurate diagnosis is challenging due to overlapping clinical and radiographic features among these entities.

Observation:

  • A unique pediatric case presented with a complex clinicopathologic profile.
  • Radiographic examination suggested a benign lesion.
  • Histopathological analysis revealed an aggressive, osteoid-producing neoplasm.

Findings:

  • The study identified unusual histologic features within the fibroosseous lesion spectrum.
  • The case demonstrated a discrepancy between radiographic and histopathological findings.

Implications:

  • This case underscores the importance of thorough histopathological evaluation for accurate diagnosis of fibroosseous gnathic lesions.
  • Understanding these unusual features is crucial for appropriate clinical management and treatment planning in pediatric patients.
  • Further research into the spectrum of fibroosseous lesions can improve diagnostic accuracy and patient outcomes.