Related Experiment Video
Updated: Apr 7, 2026

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
Published on: April 4, 2018
[Association between polymorphisms in the human dopamine D3 receptor gene and genetic susceptibility of essential
Objective:
To study the association between polymorphisms in the human dopamine D3 receptor ( DRD3 ) gene and genetic susceptibility of essential tremor in different groups.
Methods:
The DRD3 gene polymorphism in ET and health control groups were analyzed with MscI restricted fragment length polymorphism ( RFLP). The results of PCR-RFLP were analyzed by using the statistical software.
Results:
No significant differences in alleles and allele frequency of MscI site at the DRD3 gene locus were observed between healthy control and different ET groups.
Conclusion:
There is no association between polymorphisms MscI site at DRD3 and genetic susceptibility of ET.
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