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Continuous Flow Chemistry: Reaction of Diphenyldiazomethane with p-Nitrobenzoic Acid
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Continuous flow of nitroso Diels-Alder reaction

Erika Nakashima1, Hisashi Yamamoto

  • 1Department of Chemistry, The University of Chicago, 5735 South Ellis Avenue, Chicago, IL 60637, USA. nakashimaerica@uchicago.edu yamamoto@uchicago.edu.

Chemical Communications (Cambridge, England)
|July 4, 2015
PubMed
Summary

Flow chemistry enables efficient nitroso Diels-Alder reactions with cyclic dienes, yielding pure products rapidly. This method avoids byproducts and lengthy reaction times, outperforming traditional batch processes.

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