Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Raman imaging of the phycosphere reveals sharp gradients of organic matter exuded by single phytoplankton cells.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Aircraft observations of black carbon over the Yellow Sea and Seoul Metropolitan Area: Vertical profiles and air mass origin influence.

Journal of environmental sciences (China)·2026
Same author

Acoustofluidic separation of oblate spheroids from spheres using acoustic radiation torque and force.

Lab on a chip·2026
Same author

Elasto-Inertial Microfluidic Separation of Prolate Ellipsoids and Spheroids in a Coflow of Newtonian and Viscoelastic Fluids.

Analytical chemistry·2026
Same author

Elasto-Inertial Microfluidics for Particle Manipulation Using Co-flow of Newtonian and Viscoelastic Fluids.

Analytical chemistry·2026
Same author

CellTrap: an instrument-free microfluidic platform for cell-cell interactions at stochastically generated effector-to-target ratios.

RSC advances·2026

Related Experiment Video

Updated: Apr 7, 2026

Thermal Measurement Techniques in Analytical Microfluidic Devices
08:29

Thermal Measurement Techniques in Analytical Microfluidic Devices

Published on: June 3, 2015

10.2K

Acoustothermal heating of polydimethylsiloxane microfluidic system.

Byung Hang Ha1, Kang Soo Lee1, Ghulam Destgeer1

  • 1Department of Mechanical Engineering, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon 305-701, Korea.

Scientific Reports
|July 4, 2015
PubMed
Summary

Rapid heating of polydimethylsiloxane (PDMS) microchannels using sound waves was achieved. This novel microheater enables fast, controlled temperature changes for applications like rapid DNA amplification.

More Related Videos

Microfluidic Devices for Characterizing Pore-scale Event Processes in Porous Media for Oil Recovery Applications
08:38

Microfluidic Devices for Characterizing Pore-scale Event Processes in Porous Media for Oil Recovery Applications

Published on: January 16, 2018

11.3K
Polydimethylsiloxane-polycarbonate Microfluidic Devices for Cell Migration Studies Under Perpendicular Chemical and Oxygen Gradients
11:23

Polydimethylsiloxane-polycarbonate Microfluidic Devices for Cell Migration Studies Under Perpendicular Chemical and Oxygen Gradients

Published on: February 23, 2017

14.8K

Related Experiment Videos

Last Updated: Apr 7, 2026

Thermal Measurement Techniques in Analytical Microfluidic Devices
08:29

Thermal Measurement Techniques in Analytical Microfluidic Devices

Published on: June 3, 2015

10.2K
Microfluidic Devices for Characterizing Pore-scale Event Processes in Porous Media for Oil Recovery Applications
08:38

Microfluidic Devices for Characterizing Pore-scale Event Processes in Porous Media for Oil Recovery Applications

Published on: January 16, 2018

11.3K
Polydimethylsiloxane-polycarbonate Microfluidic Devices for Cell Migration Studies Under Perpendicular Chemical and Oxygen Gradients
11:23

Polydimethylsiloxane-polycarbonate Microfluidic Devices for Cell Migration Studies Under Perpendicular Chemical and Oxygen Gradients

Published on: February 23, 2017

14.8K

Area of Science:

  • Materials Science
  • Microfluidics
  • Biotechnology

Background:

  • Polydimethylsiloxane (PDMS) is a widely used material in microfluidic systems.
  • Efficient and rapid heating methods are crucial for microfluidic applications, such as polymerase chain reaction (PCR).

Purpose of the Study:

  • To investigate rapid heating of PDMS microchannels using surface acoustic waves (SAW).
  • To develop a novel microheater based on SAW-induced vibration damping in PDMS.
  • To demonstrate the application of this microheater in continuous flow polymerase chain reaction (CFPCR).

Main Methods:

  • Utilized a surface acoustic wave (SAW) microfluidic system to generate sound waves.
  • Induced vibration damping in PDMS, leading to rapid volumetric heating via leaky SAWs.
  • Measured heating rates, penetration depths, and energy conversion efficiency at various SAW frequencies.
  • Demonstrated spatiotemporal temperature control by independent actuation of interdigital transducers (IDTs).

Main Results:

  • Achieved rapid heating of PDMS exceeding 2,000 K/s.
  • Measured leaky SAW penetration depths ranging from 210 μm to 1290 μm.
  • Observed highest energy conversion efficiency around 30 MHz SAW frequency.
  • Successfully performed a two-step continuous flow polymerase chain reaction (CFPCR) for billion-fold DNA amplification in under 3 minutes.

Conclusions:

  • Developed a novel microheater leveraging SAW-induced heating in PDMS.
  • Demonstrated precise spatiotemporal temperature control for microfluidic applications.
  • The microheater facilitates ultra-fast CFPCR, significantly reducing reaction times.