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Updated: Apr 7, 2026

Controlling the Size, Shape and Stability of Supramolecular Polymers in Water
Published on: August 2, 2012
Dynamic Formation of Noncovalent Calixsalen Aggregates
Małgorzata Petryk1,2, Anna Troć3, Błażej Gierczyk1
1Department of Chemistry, Adam Mickiewicz University, Umultowska 89B, 61 614 Poznań (Poland).
Abstract:
A procedure for studying "dynamic structural behavior" of large chiral macrocycles is presented. Ion mobility MS, diffusion-ordered NMR spectroscopy (DOSY NMR), and optical rotation (OR) measurements, supported by calculations, are used together as effective complementary methods to study dynamic formation of noncovalent aggregates. It is shown that the monomer-dimer equilibrium is driven by π-π or CH-π interactions and controlled largely by the substitution pattern of the calixsalen skeleton.
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