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Look what else we found--clinically significant abnormalities detected during routine ROP screening
Chaitra Jayadev, Anand Vinekar1, Noel Bauer
1Department of Pediatric Retina, Narayana Nethralaya Postgraduate Institute of Ophthalmology, Bengaluru, Karnataka, India.
Indian Journal of Ophthalmology
|July 4, 2015
Summary
Routine eye screening for premature infants unexpectedly identified various serious conditions beyond retinopathy of prematurity (ROP). This highlights the value of digital imaging in early detection of sight-threatening infant eye diseases.
Area of Science:
- Ophthalmology
- Neonatal Care
- Medical Imaging
Background:
- Premature infants require regular eye examinations to detect conditions like retinopathy of prematurity (ROP).
- Digital imaging, such as Retcam, is increasingly used for infant eye screening.
- Serendipitous findings during ROP screening can reveal other ocular pathologies.
Purpose of the Study:
- To document the range of anterior and posterior segment diagnoses found in Asian Indian premature infants.
- To identify conditions detected incidentally during standard retinopathy of prematurity (ROP) screening.
- To assess the utility of digital ocular imaging in a premature infant population.
Main Methods:
- Retrospective review of Retcam imaging sessions from 2011.
- Inclusion criteria: infants born <2001g and/or <34.1 weeks gestation undergoing ROP screening.
- Standardized seven-image protocol including anterior segment, disc, macula, and four quadrants.
Main Results:
- 111 out of 1450 infants (7.66%) had non-ROP diagnoses.
- Anterior segment issues included cataract, lid abnormalities, anophthalmos, microphthalmos, and corneal diseases.
- Posterior segment findings included retinal hemorrhages, cherry red spots, and neonatal uveitis; two retinoblastomas were detected.
Conclusions:
- Digital ocular imaging during ROP screening can serendipitously detect significant, potentially life-threatening infant eye conditions.
- Early detection of these conditions through routine screening can lead to timely medical or surgical intervention.
- Findings support advocating for universal infant eye screening programs utilizing digital imaging.
