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Updated: Apr 7, 2026

Intralymphatic Immunotherapy and Vaccination in Mice
Published on: February 2, 2014
"In situ" vaccination for systemic effects in follicular lymphoma
Arne Kolstad1, Johanna Olweus2
1Department of Oncology; Oslo University Hospital Radiumhospitalet ; Oslo, Norway ; K.G. Jebsen Center for Cancer Immunotherapy; Institute for Clinical Medicine; University of Oslo ; Oslo, Norway.
Abstract:
Therapeutic vaccines for follicular lymphoma have had limited success. A novel in situ immunotherapeutic strategy combining 3 different treatment modalities induced regression of disseminated follicular lymphoma, which correlated with systemic antitumor T-cell immunity. These results should renew interest in the development of local combined radio- and immunotherapies to achieve abscopal effects.
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