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From Dish to Bedside: Lessons Learned While Translating Findings from a Stem Cell Model of Disease to a Clinical
John McNeish1, Jason P Gardner1, Brian J Wainger2
1Regenerative Medicine Discovery Performance Unit, GlaxoSmithKline, Cambridge, MA 02139, USA.
Cell Stem Cell
|July 4, 2015
Abstract:
While iPSCs have created unprecedented opportunities for drug discovery, there remains uncertainty concerning the path to the clinic for candidate therapeutics discovered with their use. Here we share lessons that we learned, and believe are generalizable to similar efforts, while taking a discovery made using iPSCs into a clinical trial.

