Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cell Motility through Blebbing01:16

Cell Motility through Blebbing

2.7K
Blebs are a type of membrane protrusion formed by the internal hydrostatic pressure of the cytoplasm. Blebs are observed in several cell types, including fibroblasts, immune cells, and single-celled organisms like the amoeba. The primary function of blebs is cell locomotion and apoptosis, but they are also found during necrosis and cell division. The life cycle of a bleb comprises an initiation phase followed by the expansion and retraction phases.
Blebbing Through the Matrix
In multicellular...
2.7K
Abnormal Proliferation02:23

Abnormal Proliferation

5.4K
Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the...
5.4K
Abnormal Proliferation02:23

Abnormal Proliferation

3.8K
3.8K
Cells Coordinate Growth and Proliferation02:36

Cells Coordinate Growth and Proliferation

5.3K
Cell size is a significant factor impacting cellular design, function, and fitness. There exists some internal coordination by which cells double their masses before division, thus, achieving homeostasis. Coordination between cell growth and proliferation depends on the checkpoints in between cell cycle phases. Loss of coordination or failure in the checkpoint mechanism can drive the cell to uncontrolled growth and loss of cellular function. Like dividing cells that coordinate cellular growth,...
5.3K
Cells Coordinate Growth and Proliferation02:36

Cells Coordinate Growth and Proliferation

3.3K
3.3K
Overview of Cell Signaling01:23

Overview of Cell Signaling

26.7K
Despite the protective membrane that separates a cell from the environment, cells need the ability to detect and respond to environmental changes. Additionally, cells often need to communicate with one another. Unicellular and multicellular organisms use a variety of cell signaling mechanisms to communicate with the environment.
Cells respond to many types of information, often through receptor proteins positioned on the membrane. For example, skin cells respond to and transmit touch...
26.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The origins of Michael Conrad's research programs (1964-1979).

Bio Systems·2002
Same author

The physics of symbols: bridging the epistemic cut.

Bio Systems·2001
Same author

The measurement problem in artificial world models.

Bio Systems·1989
Same author

The complementarity principle and the origin of macromolecular information.

Bio Systems·1979
Same author

Complementarity vs. reduction as explanation of biological complexity.

The American journal of physiology·1979
Same author

Physical problems of decision-making constraints.

The International journal of neuroscience·1972

Related Experiment Video

Updated: Apr 7, 2026

Mammosphere Formation Assay from Human Breast Cancer Tissues and Cell Lines
10:51

Mammosphere Formation Assay from Human Breast Cancer Tissues and Cell Lines

Published on: March 22, 2015

34.4K

Cell phenomenology: The first phenomenon.

H H Pattee1

  • 11611 Cold Spring Road, Williamstown, MA 01267, USA.

Progress in Biophysics and Molecular Biology
|July 5, 2015
PubMed
Summary

Phenomenology is redefined as the subjective consequence of physical interactions. This perspective links subjective experience to evolutionary adaptation through a primitive symbol-matter distinction, crucial for survival.

Keywords:
ComplementarityEpistemic cutEvolutionFunctionMeasurementMind-body problemOrigin of lifeSelf-replicationSubject-object problemSymbol-matter problem

More Related Videos

Phenotypic and Functional Characterization of Endothelial Colony Forming Cells Derived from Human Umbilical Cord Blood
13:46

Phenotypic and Functional Characterization of Endothelial Colony Forming Cells Derived from Human Umbilical Cord Blood

Published on: April 13, 2012

16.8K
A Mimic of the Tumor Microenvironment: A Simple Method for Generating Enriched Cell Populations and Investigating Intercellular Communication
09:52

A Mimic of the Tumor Microenvironment: A Simple Method for Generating Enriched Cell Populations and Investigating Intercellular Communication

Published on: September 20, 2016

11.0K

Related Experiment Videos

Last Updated: Apr 7, 2026

Mammosphere Formation Assay from Human Breast Cancer Tissues and Cell Lines
10:51

Mammosphere Formation Assay from Human Breast Cancer Tissues and Cell Lines

Published on: March 22, 2015

34.4K
Phenotypic and Functional Characterization of Endothelial Colony Forming Cells Derived from Human Umbilical Cord Blood
13:46

Phenotypic and Functional Characterization of Endothelial Colony Forming Cells Derived from Human Umbilical Cord Blood

Published on: April 13, 2012

16.8K
A Mimic of the Tumor Microenvironment: A Simple Method for Generating Enriched Cell Populations and Investigating Intercellular Communication
09:52

A Mimic of the Tumor Microenvironment: A Simple Method for Generating Enriched Cell Populations and Investigating Intercellular Communication

Published on: September 20, 2016

11.0K

Area of Science:

  • Philosophy of Mind
  • Evolutionary Biology
  • Cognitive Science

Background:

  • Phenomenology traditionally studies subjective conscious experience from a first-person viewpoint.
  • The philosophical movement emphasized subjective experience as the foundation of knowledge.
  • This work proposes an expanded, evolutionary and physical perspective on phenomena.

Purpose of the Study:

  • To redefine phenomena as the subjective consequence of physical interactions within an organism.
  • To explore the evolutionary origins of subjective experience and the subject-object distinction.
  • To reframe the mind-body problem as a fundamental epistemic subject-object problem.

Main Methods:

  • Conceptual analysis integrating evolutionary and physical principles.
  • Reduction of the mind-body problem to the symbol-matter problem at the origin of life.
  • Examination of self-replicating units as the earliest form of symbol-matter distinction.

Main Results:

  • Phenomena are interpreted as functional, subjective consequences of physical detection and measurement by an organism.
  • The epistemic cut (subject-object distinction) is identified as essential for the emergence of phenomena and evolutionary adaptation.
  • The first memory-based self-replicating units, like cells, represent the most primitive symbol-matter distinction.

Conclusions:

  • Subjective phenomena are intrinsically linked to physical interactions and evolutionary processes.
  • The subject-object distinction is a fundamental requirement for life's ability to adapt.
  • Understanding phenomena through an evolutionary and physical lens offers new insights into consciousness and cognition.