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Rapid maxillary expansion (RME) for pediatric obstructive sleep apnea: a 12-year follow-up
Paola Pirelli1, Maurizio Saponara2, Christian Guilleminault3
1Department of Clinical Sciences and Translational Medicine, University of Tor Vergata, Rome, Italy.
Insights
Rapid maxillary expansion (RME) offers stable, long-term relief for pediatric obstructive sleep apnea (OSA) in children with maxillary narrowing. Follow-up into adulthood confirms sustained positive outcomes and airway stability.
Area of Science:
- Orthodontics
- Pediatric Sleep Medicine
- Craniofacial Development
Background:
- Obstructive sleep apnea (OSA) in children can be associated with craniofacial abnormalities.
- Maxillary hypoplasia is a potential contributing factor to pediatric OSA.
- Rapid maxillary expansion (RME) is an orthodontic technique used to address maxillary constriction.
Purpose of the Study:
- To prospectively assess the long-term efficacy of RME in children diagnosed with OSA.
- To evaluate the stability of palatal expansion and its effect on OSA symptoms over a decade.
- To determine if RME provides sustained benefits for pediatric OSA patients with maxillary narrowing.
Main Methods:
- Thirty-one children with OSA and maxillary narrowing underwent RME.
- Twenty-three participants were followed for a mean of 12 years post-treatment.
- Long-term evaluation included clinical assessments, polysomnography (PSG), and computed tomography (CT) imaging.
Main Results:
- Clinical evaluations and questionnaire scores remained normal throughout the follow-up period.
- Polysomnography (PSG) findings were consistently normal at the 12-year mark.
- CT imaging confirmed the stability of maxillary expansion and pterygoid process distances over time.
Conclusions:
- RME treatment leads to stable, long-term positive outcomes in a subgroup of pediatric OSA patients.
- Children with isolated maxillary narrowing treated with RME show sustained improvement into adulthood.
- The study supports RME as an effective intervention for specific cases of pediatric OSA.
Objective:
The objective of this study was to prospectively evaluate the long-term efficacy of rapid maxillary expansion (RME) in a group of children with obstructive sleep apnea (OSA).
Material And Method:
Thirty-one children diagnosed with OSA were involved in the study. These children had isolated maxillary narrowing and absence of enlarged adenotonsils at baseline. Twenty-three individuals (73% of the initial group) were followed up annually over a mean of 12 years after the completion of orthodontic treatment at a mean age of 8.68 years. Eight children dropped out over time due to either moving out of the area (n = 6) or refusal to submit to regular follow-up (n = 2). Subjects underwent clinical reevaluation over time and repeat polysomnography (PSG) in the late teenage years or in their early 20s. During the follow-up period, eight children dropped out and 23 individuals (including 10 girls) underwent a final clinical investigation with PSG (mean age of 20.9 years). The final evaluation also included computerized tomographic (CT) imaging that was compared with pre- and post-initial treatment findings.
Results:
Yearly clinical evaluations, including orthodontic and otolaryngological examinations and questionnaire scores, were consistently normal over time, and PSG findings remained normal at the 12-year follow-up period. The stability and maintenance of the expansion over time was demonstrated by the maxillary base width and the distance of the pterygoid processes measured using CT imaging.
Conclusion:
A subgroup of OSA children with isolated maxillary narrowing initially and followed up into adulthood present stable, long-term results post RME treatment for pediatric OSA.
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