Related Experiment Video
Updated: Apr 7, 2026
10:35
Microvascular Decompression: Salient Surgical Principles and Technical Nuances
Published on: July 5, 2011
47.6K
[Kawasaki disease and cranial nerve involvement: two cases]
M-C Delafay1, Z Matoussi2, V Remy-Piccolo3
1Service de pédiatrie, hôpital Nord, CHU de Saint-Étienne, avenue Albert-Raymond, 42055 Saint-Étienne, France.
Summary
Kawasaki disease (KD) rarely affects the central nervous system (CNS). This report details two rare KD cases with cranial nerve inflammation, successfully treated with IV immunoglobulins.
Area of Science:
- Neurology
- Pediatrics
- Immunology
Background:
- Kawasaki disease (KD) is a pediatric vasculitis.
- Central nervous system (CNS) involvement in KD is uncommon, typically limited to lymphocytic meningitis.
- Atypical neurological manifestations of KD are rare and diagnostically challenging.
Observation:
- Two pediatric patients presented with unusual CNS manifestations of KD.
- Case 1 exhibited supranuclear vertical gaze palsy.
- Case 2 developed Bell palsy (facial nerve palsy).
Findings:
- Both patients received intravenous immunoglobulin (IVIG) therapy.
- Neurological symptoms resolved favorably and rapidly following IVIG administration.
- No long-term sequelae were observed in either case.
Implications:
- This report expands the spectrum of rare CNS manifestations in Kawasaki disease.
- Early recognition and treatment of atypical KD are crucial to prevent delayed diagnosis and potential complications.
- The findings underscore the need for heightened clinical suspicion for KD in children presenting with unexplained neurological deficits.
More Related Videos
Related Concept Videos
01:22Cranial Nerves: Types Part II
6.0K
Cranial nerves are responsible for transmitting motor and sensory information between the brain and various parts of the body. There are twelve pairs of cranial nerves. While the first six innervate the head and neck, the latter six nerves innervate the head and neck, as well as organs and tissues in the thoracic and abdominal cavities. They facilitate communication, expression, and autonomic control within the human body.
Facial Nerve (Cranial Nerve VII)
Cranial nerve VII, or the facial nerve,...
Facial Nerve (Cranial Nerve VII)
Cranial nerve VII, or the facial nerve,...
6.0K
01:14Cranial Nerves: Types Part I
6.5K
Cranial nerves are responsible for transmitting motor and sensory information between the brain and various parts of the body. There are twelve pairs of cranial nerves, with the first six being essential in sensory perception, motor control, and autonomic functions related to the head and neck.
Olfactory Nerve (Cranial Nerve I)
The olfactory nerve, or cranial nerve I, is unique as it is purely sensory and dedicated to the sense of smell. This nerve originates in the olfactory epithelium of the...
Olfactory Nerve (Cranial Nerve I)
The olfactory nerve, or cranial nerve I, is unique as it is purely sensory and dedicated to the sense of smell. This nerve originates in the olfactory epithelium of the...
6.5K
01:19Cranial Nerves: Overview and Anatomy
6.0K
The cranial nerves are an important part of the complex network of nerves in the human body. These nerves emerge directly from the brain and are responsible for transmitting essential information between the brain and various parts of the head and neck. There are 12 pairs of cranial nerves, systematically numbered using Roman numerals from I to XII, beginning from the anterior and moving to the posterior of the brain. Each cranial nerve is uniquely identified by names that reflect its function...
6.0K
01:19Cranial and Spinal Meninges
4.9K
The cranial and spinal meninges are complex protective structures surrounding the central nervous system (CNS), consisting of the brain and spinal cord. These meninges consist of the dura mater, the arachnoid mater, and the pia mater. They protect the CNS, provide structural support, and aid in circulating cerebrospinal fluid (CSF).
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...
4.9K
01:28Diphtheria
97
Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...
97
01:21Aneurysm II: Clinical Manifestations and Diagnostic Studies
537
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
537