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Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
Published on: December 21, 2019
Review: New diagnostic and therapeutic avenues for mesothelioma
Usman Zafar Paracha1, Khezar Hayat2, Muhammad Ali2
1School of Pharmacy, Hajvery University, Lahore, Pakistan.
Abstract:
Mesothelioma is a rare form of cancer affecting the mesothelium lining. It is usually caused by asbestos exposure or exposure to nanofibers. Median survival is less than one year in the mesothelioma patients. Due to its severity, there is a dire necessity to find out new diagnostic and therapeutic strategies. Some recent strategies could help us in fighting against mesothelioma. Diagnostic tools include a range of biomarkers or biotechnological procedure. Therapeutic tools include chemotherapeutic strategies along with immunotherapy, gene therapy and alternative therapy.
Insights
Mesothelioma, a rare cancer linked to asbestos, has a poor prognosis. New diagnostic tools and therapies like immunotherapy offer hope for fighting this aggressive disease.
Area of Science:
- Oncology
- Environmental Health
Background:
- Mesothelioma is a rare cancer of the mesothelium.
- It is primarily caused by asbestos or nanofiber exposure.
- The median survival for mesothelioma patients is less than one year.
Purpose of the Study:
- To review recent advancements in diagnosing and treating mesothelioma.
- To highlight the urgent need for improved strategies against this severe cancer.
Main Methods:
- Review of current diagnostic tools, including biomarkers and biotechnological procedures.
- Overview of therapeutic strategies, encompassing chemotherapy, immunotherapy, gene therapy, and alternative treatments.
Main Results:
- Emerging diagnostic methods show promise for earlier detection.
- Novel therapeutic approaches, including immunotherapy and gene therapy, are being explored.
- A combination of strategies may be necessary for effective mesothelioma management.
Conclusions:
- Significant progress is being made in mesothelioma diagnostics and therapeutics.
- Continued research into biomarkers and advanced therapies is crucial.
- Addressing the challenges of mesothelioma requires a multi-faceted approach.
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