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Updated: Apr 7, 2026
06:20
Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
Published on: March 11, 2021
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Target development for diversified irradiations at a medical cyclotron.
S Spellerberg1, B Scholten1, I Spahn1
1Institut für Neurowissenschaften und Medizin, INM-5: Nuklearchemie, Forschungszentrum Jülich, D-52425 Jülich, Germany.
Summary
The upgraded medical cyclotron facility now produces essential radionuclides like Selenium-75 and Iodine-120/124 for local use. This enhancement improves the cyclotron
Area of Science:
- Nuclear Physics
- Radiochemistry
- Medical Cyclotron Applications
Background:
- Existing medical cyclotron facility with proton and deuteron beams.
- Need for enhanced radionuclide production capabilities.
Purpose of the Study:
- Upgrade irradiation facility for improved beam quality and targetry.
- Assess production of no-carrier-added radionuclides.
- Enhance the utility of the medical cyclotron.
Main Methods:
- Extended beam line and incorporated solid-state targetry.
- Performed beam quality tests.
- Conducted nuclear data measurements.
- Improved radiochemical separation techniques.
Main Results:
- Successfully produced radionuclides such as Selenium-75, Iodine-120, and Iodine-124.
- Achieved production in no-carrier-added form using solid targets at a 20° slant angle.
- Utilized medium beam currents up to 20 µA.
- Obtained sufficient quantities for local use.
Conclusions:
- The upgraded irradiation facility significantly enhances the medical cyclotron's utility.
- The facility is now capable of producing valuable radionuclides for local applications.
- Improvements in beam delivery and targetry enable efficient radionuclide synthesis.
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