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[Epidemiology of preterm birth: Prevalence, recent trends, short- and long-term outcomes]
H Torchin1, P-Y Ancel2, P-H Jarreau3
1Équipe de recherche en épidémiologie obstétricale, périnatale et pédiatrique, Inserm U1153, centre de recherche d'épidémiologie et statistique, Sorbonne Paris-Cité, bâtiment Port-Royal, 53, avenue de l'Observatoire, 75014 Paris, France; DHU risques et grossesse, 53, avenue de l'Observatoire, 75014 Paris, France.
Insights
Globally, 15 million babies are born preterm annually. Careful monitoring of all preterm infants is crucial due to significant risks of mortality and long-term disabilities, varying by gestational age.
Area of Science:
- Neonatal Medicine
- Pediatric Health
- Public Health
Context:
- Preterm birth affects approximately 15 million newborns globally each year, with rates around 11%.
- Preterm infants are categorized by gestational age: moderate (32-36 weeks), very (28-31 weeks), and extremely preterm (<28 weeks).
- While neonatal mortality is declining, it remains substantial and is strongly linked to gestational age at birth.
Purpose:
- To highlight the critical need for monitoring all preterm infants, regardless of gestational age.
- To underscore the importance of understanding the prognosis and potential outcomes for preterm babies.
- To address the significant disparities in care and outcomes between and within countries.
Summary:
- Preterm birth, occurring before 37 weeks of gestation, impacts millions worldwide annually.
- Neonatal mortality and severe morbidities, including developmental disabilities, are significantly higher in preterm infants and increase with lower gestational age.
- The risk of motor or cognitive impairment is notably higher even in late preterm infants (34-36 weeks) compared to full-term infants.
Impact:
- Emphasizes the necessity for vigilant monitoring and care for all preterm infants to mitigate risks.
- Promotes greater awareness among healthcare professionals regarding the diverse outcomes and prognoses associated with preterm birth.
- Calls attention to the global and national inequities in healthcare access and outcomes for preterm infants.
Abstract:
Every year, approximately 15 million babies are born preterm worldwide (before 37 completed weeks of gestation), putting the global preterm birth rate at 11%; they are about 60,000 in France. About 85% of these births are moderate (32-33 weeks) to late preterm babies (34-36 weeks), 10% are very preterm babies (28-31 weeks) and 5% are extremely preterm babies (< 28 weeks). Though neonatal mortality rates are dropping, they remain high and are largely determined by gestational age at birth (over 10% mortality for infants born before 28 weeks, 5-10% at 28-31 weeks and 1-2% at 32-34 weeks). Severe neonatal morbidity and disabilities during childhood are also frequent and vary with gestational age. For example, the risk of motor or cognitive impairment is 2 to 3 times higher among children born between 34 and 36 weeks than among children born full-term. Therefore, every preterm baby must be carefully monitored. Recent cohort studies have focused on extremely preterm births; however, awareness of potential outcome and prognosis of all preterm babies is a crucial step for health professionals caring for these children. Huge disparities exist between high- and low-income countries, but also among high-income countries themselves.
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