Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Oral microbiota characteristics in children younger than 3 years with febrile seizures: a prospective observational study.

BMC microbiology·2026
Same author

Comparative effectiveness of horticultural therapy modalities for cognitive function and depressive symptoms in older adults with cognitive impairment: Protocol for a systematic review and network meta-analysis.

PloS one·2026
Same author

GIGEM (Group Isolation Gauge Effect Metrics), a Software Suite for Analyzing Social Isolation-induced Sleep Loss and Multi-batch Experiments in <i>Drosophila</i>.

Journal of biological rhythms·2026
Same author

Hyperthermia combined with intraperitoneal perfusion of drugs improves malignant ascites caused by gastrointestinal tumors by reshaping the tumor immune microenvironment.

Anti-cancer drugs·2026
Same author

RPL26 UFMylation deficiency triggers Paneth cell apoptosis associated with ER stress by impairing ATG16L1-dependent ER-phagy.

Cellular signalling·2026
Same author

SI-traceable purity assignment for peptide sublancin using mass balance approach and isotope dilution mass spectrometry based on amino acid analysis.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences·2026
Same journal

Vasopressin type-2 receptor mRNA expressions in endolymphatic sac and temporal bone cT findings in Meniere's disease.

Acta oto-laryngologica·2026
Same journal

The impact of climate and environmental factors on the incidence of Bell's palsy: a nationwide population study.

Acta oto-laryngologica·2026
Same journal

Association between low temporalis muscle thickness and chemoradiotherapy-induced leukopenia in head and neck squamous cell carcinoma.

Acta oto-laryngologica·2026
Same journal

Auditory Outcomes After Simultaneous Translabyrinthine Vestibular Schwannoma Resection and Cochlear Implantation: A Prospective Case Series.

Acta oto-laryngologica·2026
Same journal

CT imaging parameters of the oval window region can predict the extent of stapes footplate exposure in patients with otosclerosis.

Acta oto-laryngologica·2026
Same journal

Congenital middle ear anomalies: endoscopic outcomes, facial nerve anomalies, and bilateral consistency in 41 ears.

Acta oto-laryngologica·2026
See all related articles

Related Experiment Video

Updated: Apr 7, 2026

Reversible Cooling-induced Deactivations to Study Cortical Contributions to Obstacle Memory in the Walking Cat
09:43

Reversible Cooling-induced Deactivations to Study Cortical Contributions to Obstacle Memory in the Walking Cat

Published on: December 11, 2017

7.4K

Scopolamine attenuates auditory cortex response.

Anchun Deng1, Xiaojun Liang1, Yuchen Sun2

  • 1a 1 Department of Otolaryngology Head and Neck Surgery, Xinqiao Hospital, Third Military Medical University , Chongqing, PR China.

Acta Oto-Laryngologica
|July 7, 2015
PubMed
Summary
This summary is machine-generated.

Scopolamine reduced auditory cortex responses to sound gaps in rats, suggesting it may help manage tinnitus by decreasing neural hyperexcitability.

Keywords:
Scopolamineacetylcholineauditory cortexgap detectiontinnitus

More Related Videos

Combined Shuttle-Box Training with Electrophysiological Cortex Recording and Stimulation as a Tool to Study Perception and Learning
08:43

Combined Shuttle-Box Training with Electrophysiological Cortex Recording and Stimulation as a Tool to Study Perception and Learning

Published on: October 22, 2015

10.9K
Stereotactically-guided Ablation of the Rat Auditory Cortex, and Localization of the Lesion in the Brain
09:29

Stereotactically-guided Ablation of the Rat Auditory Cortex, and Localization of the Lesion in the Brain

Published on: October 11, 2017

12.3K

Related Experiment Videos

Last Updated: Apr 7, 2026

Reversible Cooling-induced Deactivations to Study Cortical Contributions to Obstacle Memory in the Walking Cat
09:43

Reversible Cooling-induced Deactivations to Study Cortical Contributions to Obstacle Memory in the Walking Cat

Published on: December 11, 2017

7.4K
Combined Shuttle-Box Training with Electrophysiological Cortex Recording and Stimulation as a Tool to Study Perception and Learning
08:43

Combined Shuttle-Box Training with Electrophysiological Cortex Recording and Stimulation as a Tool to Study Perception and Learning

Published on: October 22, 2015

10.9K
Stereotactically-guided Ablation of the Rat Auditory Cortex, and Localization of the Lesion in the Brain
09:29

Stereotactically-guided Ablation of the Rat Auditory Cortex, and Localization of the Lesion in the Brain

Published on: October 11, 2017

12.3K

Area of Science:

  • Neuroscience
  • Pharmacology

Background:

  • Tinnitus is often associated with cortical hyperexcitability.
  • Muscarinic acetylcholine receptor antagonists, like scopolamine, may offer therapeutic potential.

Purpose of the Study:

  • Investigate scopolamine's effects on the auditory cortex (AC) and inferior colliculus (IC) in awake rats.
  • Understand the drug's potential impact on tinnitus and gap detection mechanisms.

Main Methods:

  • Recorded AC and IC field potentials in rats exposed to silent gaps in noise.
  • Administered scopolamine (3 mg/kg, i.m.) and observed changes in neural responses.

Main Results:

  • Scopolamine significantly reduced AC responses to gap offsets.
  • No significant effect on IC responses was observed.
  • Results indicate scopolamine may decrease neural synchrony in the auditory cortex.

Conclusions:

  • Scopolamine's reduction of AC responses to gap offsets may counteract tinnitus-related hyperexcitability.
  • The drug's effects suggest a potential therapeutic role in managing tinnitus.