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Multivessel Percutaneous Coronary Interventions in the United States: Insights From the Nationwide Inpatient Sample
Shilpkumar Arora1, Sidakpal S Panaich2, Nileshkumar J Patel3
1Internal Medicine Department, Mount Sinai St Luke's Roosevelt Hospital, New York, NY, USA.
Insights
Multivessel percutaneous coronary intervention (MVPCI) is linked to increased in-hospital mortality and costs compared to single-vessel procedures. Higher-volume hospitals demonstrate better outcomes for MVPCI patients.
Area of Science:
- Cardiology
- Interventional Cardiology
- Health Services Research
Background:
- Multivessel coronary artery disease (CAD) poses a significant mortality risk.
- Comprehensive data on in-hospital outcomes after multivessel percutaneous coronary intervention (MVPCI) are limited.
Purpose of the Study:
- To analyze in-hospital outcomes following MVPCI.
- To identify predictors of mortality and complications after MVPCI.
Main Methods:
- Utilized the Healthcare Cost and Utilization Project's Nationwide Inpatient Sample (NIS) from 2006-2011.
- Analyzed in-hospital all-cause mortality and a composite of mortality and periprocedural complications.
- Employed multivariate analysis to identify outcome predictors.
Main Results:
- Overall in-hospital mortality post-MVPCI was 0.73%.
- Key predictors of adverse outcomes included advanced age, female sex, acute myocardial infarction, shock, comorbidities, and emergent procedure status.
- MVPCI was associated with higher mortality, length of stay (LOS), and costs compared to single-vessel PCI.
Conclusions:
- MVPCI is associated with increased in-hospital mortality, LOS, and costs relative to single-vessel PCI.
- Higher-volume hospitals reported lower mortality rates, shorter LOS, and reduced hospitalization costs for MVPCI.
Background:
Multivessel coronary artery disease carries significant mortality risk. Comprehensive data on inhospital outcomes following multivessel percutaneous coronary intervention (MVPCI) are sparse.
Methods:
We queried the Healthcare Cost and Utilization Project's nationwide inpatient sample (NIS) between 2006 and 2011 using different International Classification of Diseases, 9th Revision, Clinical Modification procedure codes. The primary outcome was inhospital all-cause mortality, and the secondary outcome was a composite of inhospital mortality and periprocedural complications.
Results:
The overall mortality was low at 0.73% following MVPCI. Multivariate analysis revealed that (odds ratio, 95% confidence interval, P value) age (1.63, 1.48-1.79; <.001), female sex (1.19, 1.00-1.42; P = .05), acute myocardial infarction (AMI; 2.97, 2.35-3.74; <.001), shock (17.24, 13.61-21.85; <.001), a higher burden of comorbidities (2.09, 1.32-3.29; .002), and emergent/urgent procedure status (1.67, 1.30-2.16; <.001) are important predictors of primary and secondary outcomes. MVPCI was associated with higher mortality, length of stay (LOS), and cost of care as compared to single vessel single stent PCI.
Conclusion:
MVPCI is associated with higher inhospital mortality, LOS, and hospitalization costs compared to single vessel, single stent PCI. Higher volume hospitals had lower overall postprocedural mortality rate along with shorter LOS and lower hospitalization costs following MVPCI.
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