Related Experiment Video
Updated: Apr 7, 2026

Quantitative Mass Spectrometric Profiling of Cancer-cell Proteomes Derived From Liquid and Solid Tumors
Published on: February 27, 2015
Cancer proteomics: developments in technology, clinical use and commercialization
Nai Chien Yeat1, Charlotte Lin, Monica Sager
1Rare Genomics Institute, 4100 Forest Park, St. Louis, MO 63108, USA.
Advances in proteomics enable molecular cancer classification for earlier diagnosis and targeted treatments. This review covers technological progress, biomarker discoveries, and clinical applications in cancer diagnostics.
Area of Science:
- Biochemistry
- Molecular Biology
- Oncology
Background:
- Genomic, transcriptomic, and proteomic technologies have revolutionized cancer research.
- Molecular profiling allows for precise cancer classification.
- This molecular taxonomy promises improved diagnostics and therapeutics.
Purpose of the Study:
- To review technological advancements in proteomics for cancer research.
- To highlight recent discoveries in proteomic cancer biomarkers.
- To discuss the clinical application and commercialization trends of proteomics in cancer diagnostics.
Main Methods:
- Review of recent technological developments in proteomics.
- Analysis of proteomic cancer biomarker research findings.
- Examination of trends in clinical proteomics applications.
Main Results:
- Significant progress in proteomic technologies.
- Identification of novel proteomic biomarkers for cancer.
- Emerging clinical applications and successful commercialization examples.
Conclusions:
- Proteomics is crucial for molecular cancer subtyping and diagnostics.
- Future directions point towards enhanced cancer detection and personalized medicine.
- Continued innovation in proteomics will drive advancements in oncology.
More Related Videos
13:01Industrialized, Artificial Intelligence-guided Laser Microdissection for Microscaled Proteomic Analysis of the Tumor Microenvironment
Published on: June 3, 2022
10:37Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification
Published on: November 15, 2017
Related Concept Videos
Targeted Cancer Therapies
There are several types of targeted therapies against...
Targeted Cancer Therapies
Cancer
Cancer Survival Analysis
Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Cancer Therapies