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Analysis of complications after blood components' transfusions
Polski Przeglad Chirurgiczny
|July 7, 2015
Summary
Early complications from blood transfusions are common, particularly febrile nonhemolytic and allergic reactions. Platelet concentrate transfusions showed a higher incidence of these adverse events compared to PRBC and FFP.
Area of Science:
- Transfusion Medicine
- Hematology
- Clinical Pathology
Background:
- Adverse reactions to blood components remain a significant clinical challenge.
- These complications can limit the application of liberal transfusion strategies.
Purpose of the Study:
- To determine the 5-year incidence of early blood transfusion complications.
- To evaluate the relationship between transfusion reactions and specific blood components.
Main Methods:
- Retrospective analysis of 58,505 blood component transfusions from 2006-2010.
- Data collection on transfusion volumes and reported adverse reactions to the Regional Blood Donation and Treatment Center (RBDTC).
Main Results:
- 95 adverse transfusion reactions were reported (0.16% of all transfusions).
- Febrile nonhemolytic reactions (36.8%) and allergic reactions (30.5%) were the most frequent complications.
- Platelet concentrate transfusions were associated with more reactions than PRBC and FFP transfusions.
Conclusions:
- Febrile nonhemolytic and allergic reactions are the most common transfusion complications.
- Platelet concentrate transfusions exhibit a higher rate of these complications compared to PRBC and FFP.
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