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Monovalent cation specificity of passive transport mediated by laidlomycin and 26-deoxylaidlomycin
U Gräfe1, G Reinhardt, N Miosga
1Akademie der Wissenschaften der DDR, Zentral-institut für Mikrobiologie und experimentelle Therapie, Jena.
Journal of Basic Microbiology
|January 1, 1989
Abstract:
The capacity of laidlomycin (I) and the new 26-deoxylaidlomycin (II) to facilitate passive fluxes of cations through a layer of organic solvent (CHCl3/n-heptane) was estimated in comparison to monensin A (III). While II displayed a 10fold higher transport rate for sodium as compared to calcium, laidlomycin (I) was distinguishable by mediating approx. 100 times lower conveyance of the divalent cations.