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Updated: Jul 28, 2026

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
Published on: March 1, 2015
[Medication-induced dysphagia : A review]
C Schwemmle1, M Jungheim, S Miller
1HNO-Klinik, Arbeitsbereich Phoniatrie, Pädaudiologie, klinische Audiologie, Otto-von-Guericke-Universität Magdeburg, Leipziger Str. 44, 39120, Magdeburg, Deutschland, cornelia.schwemmle@med.ovgu.de.
Medication can significantly impact swallowing function, leading to dysphagia, especially in older adults with polypharmacy. Reviewing and adjusting medications is crucial for managing this often-overlooked condition.
Area of Science:
- Gerontology
- Pharmacology
- Medicine
Context:
- Swallowing (deglutition) is a complex physiological process.
- Dysphagia, or swallowing difficulties, can arise from various factors including anatomical changes, surgery, and neuromuscular disorders.
- Age-related changes (presbyphagia) and polypharmacy can exacerbate swallowing issues.
Purpose:
- To highlight the underrecognized impact of medications on swallowing function.
- To emphasize the prevalence of medication-induced dysphagia, particularly in elderly patients.
- To review drug classes with direct or indirect negative effects on swallowing.
Summary:
- Medication-associated dysphagia is frequently overlooked, despite numerous drugs potentially impairing swallowing.
- Polypharmacy in older adults increases the risk of drug interactions affecting deglutition.
- Management involves medication review, dose adjustment, administration guidance, and therapeutic interventions like swallowing training.
Impact:
- Increases awareness among healthcare professionals about medication-induced dysphagia.
- Promotes critical evaluation of medication regimens in patients with swallowing difficulties.
- Encourages proactive management strategies to improve patient outcomes and quality of life.
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