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Additives and Fillers in Concrete01:29

Additives and Fillers in Concrete

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Additives and fillers are integral to enhancing the properties of concrete. Pozzolans and blast-furnace slag are additives or admixtures due to their reactions with calcium hydroxide released during cement hydration. Fillers, which are finely ground and similar in fineness to Portland cement, improve concrete attributes such as workability density, and reduce capillary bleeding or cracking. Some fillers possess hydraulic properties or participate in benign reactions within the cement paste.
The...
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Pharmaceutical products contain more than just the active drug; they also contain various excipients such as binders, solubilizers, stabilizers, preservatives, and other elements. In some cases, impurities or contaminants might be present. Traditionally, quality control in pharmaceuticals has primarily focused on the analysis of the active drug, often overlooking the impact of these additional components. The recent issue with heparin contamination by over-sulfated chondroitin sulfate, a...
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Sedatives and hypnotics encompass a wide range of substances, each with its unique mechanism of action, uses, and potential adverse effects.
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Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
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[Fillers and associated side effects].

M Heppt1, D Hartmann, M Reinholz

  • 1Klinik und Poliklinik für Dermatologie und Allergologie, Klinikum der Universität München (LMU), Frauenlobstr. 9-11, 80337, München, Deutschland, Markus.Heppt@med.uni-muenchen.de.

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|July 8, 2015
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Summary
This summary is machine-generated.

Dermal fillers, including temporary hyaluronic acid and permanent silicone, are used for tissue augmentation. Understanding filler types and potential complications like nodules is crucial for safe and effective cosmetic treatments.

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Area of Science:

  • Dermatology
  • Biomaterials Science

Context:

  • Dermal fillers are widely used for aesthetic procedures like tissue augmentation and skin rejuvenation.
  • These biomaterials form a heterogeneous group with diverse properties and applications.

Purpose:

  • To provide a comprehensive overview and classification of commonly injected filler materials.
  • To detail filler-related complications and their therapeutic management.

Summary:

  • Fillers are categorized by degradability: temporary (e.g., hyaluronic acid), semi-permanent, and permanent (e.g., silicone).
  • Temporary fillers degrade within months, while permanent fillers carry risks of severe, irreversible side effects.
  • Common adverse events include pigmentation changes, edema, and deformities; nodules may indicate accumulation, granuloma, or infection.

Impact:

  • Knowledge of filler properties is essential for safe and effective clinical application.
  • Early identification of adverse effects is key to preventing severe complications and optimizing aesthetic outcomes.