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Kingella kingae infections in children
Nicola Principi1, Susanna Esposito2
1Pediatric Highly Intensive Care Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy. nicola.principi@unimi.it.
BMC Infectious Diseases
|July 8, 2015
Summary
Kingella kingae is an emerging pathogen in children, often causing bone and joint infections. Increased awareness and diagnostic efforts are crucial for timely treatment and preventing outbreaks.
Area of Science:
- Pediatric Infectious Diseases
- Microbiology
- Clinical Pediatrics
Background:
- Kingella kingae is increasingly recognized as a significant pathogen in infants and young children.
- Despite its prevalence, awareness within the pediatric community remains low.
- Advances in diagnostics have improved detection of this organism.
Purpose of the Study:
- To review current knowledge on Kingella kingae infections in children.
- To cover epidemiology, transmission, clinical presentation, diagnosis, and treatment.
- To highlight the need for increased awareness and diagnostic focus.
Main Methods:
- Literature review of Kingella kingae infections.
- Synthesis of data on epidemiology and clinical features.
- Analysis of diagnostic and treatment strategies.
Main Results:
- Kingella kingae commonly colonizes the oropharynx and can cause child-to-child transmission and outbreaks.
- Invasive infections predominantly affect children aged 6 months to 4 years, primarily involving joints and bone.
- Diseases are often mild, mimicking other conditions, and generally respond to antibiotics, though resistance is noted.
Conclusions:
- Kingella kingae infections require greater recognition by pediatricians and systematic laboratory investigation.
- Early identification and appropriate treatment are essential to prevent severe complications.
- Education is key to reducing outbreaks and improving patient outcomes.
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