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The mass analyzer is a crucial component of the mass spectrometer. In the ionization chamber, the vaporized sample is bombarded with a high-energy electron beam to generate a radical cation and further fragment into neutral molecules, radicals, and cations. A series of negatively charged accelerator plates accelerate the cations into the mass analyzer. The mass analyzer separates ions according to their mass-to-charge (m/z) ratios and then directs them to the detector. The common types of mass...
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Xenbase: Core features, data acquisition, and data processing.

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Summary
This summary is machine-generated.

Xenbase is a comprehensive database for Xenopus research, integrating genomic and biological data to accelerate discoveries in human disease. It provides bioinformatics tools and curated data, linking Xenopus research to human health.

Keywords:
Xenopusbiocurationgene expressiongenomicshuman disease modelingmodel organism databasephenotypes

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Area of Science:

  • Comparative genomics
  • Developmental biology
  • Biomedical research

Background:

  • Xenopus frogs are vital vertebrate models in biomedical research.
  • Xenbase serves as a central repository for extensive Xenopus data.
  • Integrating diverse genomic and biological data is crucial for advancing research.

Purpose of the Study:

  • To accelerate scientific discovery by connecting Xenopus molecular pathways with human disease.
  • To provide a user-friendly, cloud-based resource for querying and linking diverse data types.
  • To enhance the value of Xenopus data through integration, curation, and bioinformatics tools.

Main Methods:

  • Data acquisition via automated pipelines for parsing and storage.
  • Development of a relational database with a user-friendly interface.
  • Integration of gene expression curation, bioinformatics tools, and community-submitted data.
  • Data sharing with major biomedical organizations like NCBI, UniProtKB, and Ensembl.

Main Results:

  • Xenbase provides easy querying and linking of diverse data types, overcoming previous limitations.
  • Enhanced data value through high-quality gene expression curation and integration.
  • Bioinformatics tools optimized for Xenopus experiments are available.
  • Xenopus data is linked to other model organisms and human data.

Conclusions:

  • Xenbase is an essential, accessible resource accelerating biomedical research through integrated Xenopus data.
  • The database facilitates novel connections between Xenopus and human disease pathways.
  • Continuous data updates and community contributions ensure Xenbase remains a valuable, evolving resource.