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Updated: Oct 9, 2026

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
Acute ischemic stroke in a child due to basilar artery occlusion treated successfully with a stent retriever
Luis Savastano1, Joseph J Gemmete2, Aditya S Pandey2
1Department of Neurosurgery, University of Michigan Health System, Ann Arbor, Michigan, USA.
Insights
Pediatric ischemic stroke is rare. Mechanical thrombectomy using a stent retriever offers a safe and effective treatment option for acute ischemic stroke in children, as demonstrated in a case of basilar artery occlusion.
Area of Science:
- Pediatric Neurology
- Interventional Neuroradiology
- Vascular Neurology
Background:
- Childhood ischemic stroke is uncommon, with intravenous thrombolysis using tissue plasminogen activator (tPA) being the primary treatment, despite limited safety and efficacy data.
- Mechanical thrombectomy is emerging as a viable alternative for acute ischemic stroke in pediatric patients.
Observation:
- A 22-month-old child presented with an acute ischemic stroke caused by basilar artery occlusion.
Findings:
- The child was successfully treated with mechanical thrombectomy utilizing a stent retriever.
- This case highlights the potential of endovascular techniques in managing pediatric stroke.
Implications:
- Mechanical thrombectomy represents a promising and effective treatment modality for acute ischemic stroke in children.
- Further research into endovascular approaches for pediatric stroke is warranted to establish safety and efficacy profiles.
Abstract:
Ischemic strokes in childhood are rare. Thrombolytic therapy with intravenous (IV) tissue plasminogen activator (tPA) has been the main intervention for the management of pediatric stroke patients, but safety data are lacking and efficacy has been questioned. Recently, successful endovascular treatments for acute ischemic stroke in children have been reported with increasing frequency, suggesting that mechanical thrombectomy can be a safe and effective treatment. We present the case of a 22-month-old child with acute ischemic stroke due to basilar artery occlusion that was successfully treated with a stent retriever.
Related Concept Videos
Ischemic Stroke l: Introduction
Ischemic Stroke ll: Pathophysiology

