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SBA-15 Mesoporous Silica Modified with Gallic Acid and Evaluation of Its Cytotoxic Activity
Dawid Lewandowski1, Piotr Ruszkowski2, Anita Pińska2
1Faculty of Chemistry, Adam Mickiewicz University, Poznan, Poland.
Plos One
|July 8, 2015
Abstract:
Gallic acid has been covalently conjugated to SBA-15 mesoporous silica surface through different linkers. Cytotoxic activity of the hybrid organic-inorganic systems against HeLa and KB cell lines has been analyzed. Up to 67% of HeLa or KB tumor cells growth inhibition has been achieved at low silica concentration used (10 μg mL(-1)).
