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Treatment resistant somatic delusions in bipolar disorder
Hannah Slattery1, Michael Nance2
1Flinders Medical Centre, Bedford Park, South Australia, Australia.
BMJ Case Reports
|July 9, 2015
Summary
Fixed somatic delusions complicating bipolar disorder showed partial response to clozapine and electroconvulsive therapy. This suggests a link between somatic delusions and affective disorders in patients.
Area of Science:
- Psychiatry
- Neurology
Background:
- Bipolar disorder is a mood disorder characterized by significant mood fluctuations.
- Somatic delusions, fixed false beliefs about bodily functioning, can complicate psychiatric conditions.
Observation:
- Two patients with bipolar disorder developed fixed somatic delusions.
- These delusions persisted despite treatment with various antidepressant and antipsychotic medications.
Findings:
- Both patients showed a partial response to clozapine treatment.
- Electroconvulsive therapy (ECT) also resulted in partial symptom improvement.
- Treatment led to resolution of mood symptoms and reduced somatic preoccupation.
Implications:
- Clozapine and ECT may be viable treatment options for somatic delusions in bipolar disorder.
- The findings suggest a potential relationship between somatic delusions and affective disorders, warranting further investigation.
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