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Effect of Trigonella foenum-graecum and Ammi majus on calcium oxalate urolithiasis in rats
S K Ahsan1, M Tariq, A M Ageel
1Research Centre, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Journal of Ethnopharmacology
|October 1, 1989
Abstract:
The present study was undertaken to investigate the effect of Trigonella foenum-graecum seed and Ammi majus fruit on experimentally-induced kidney stones. Oxalate urolithiasis in male rats was produced by the addition of 3% glycolic acid to their diet. After 4 weeks, highly significant deposition in the kidneys was noticed and changes in water intake and body weight recorded. Daily oral treatment with T. foenum-graecum significantly decreased the quantity of calcium oxalate deposited in the kidneys thus supporting its use in Saudi folk medicine. The effects obtained by A. majus were, however, not significant.