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Updated: Apr 7, 2026

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
Published on: August 26, 2025
Transcatheter pulmonary embolectomy after fontan
Rachel D Torok1,2, Gregory A Fleming1,2, Kevin D Hill1,2
1Division of Pediatric Cardiology, Duke University Medical Center, Durham, North Carolina.
Pulmonary embolism (PE) treatment can be challenging. A young woman with Fontan circulation successfully underwent AngioVac aspiration thrombectomy for a severe saddle PE after failing thrombolytic therapy.
Area of Science:
- Cardiology
- Interventional Cardiology
- Vascular Surgery
Background:
- Pulmonary embolism (PE) is a leading cause of death in hospitalized patients.
- Thrombolytic therapy is the standard treatment for PE.
- Catheter-based interventions offer alternatives for patients unsuitable for thrombolysis.
Observation:
- A 22-year-old woman with Fontan circulation developed severe postpartum cardiomyopathy and a saddle PE.
- The patient failed to respond to thrombolytic therapy.
Findings:
- Successful pulmonary embolectomy was achieved using the AngioVac aspiration system.
- This case highlights the AngioVac system's efficacy in managing complex PE.
Implications:
- Patients with Fontan circulation have a higher risk of thromboembolic events.
- AngioVac thrombectomy is a viable and effective option for PE in complex cardiac patients.
- This approach may reduce the need for surgical embolectomy in select populations.
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