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Adult idiopathic hypertrophic pyloric stenosis
Hsien-Ping Lin1, Yu-Chiang Lin2, Chen-Yun Kuo3
1Division of Gastroenterology, Department of Internal Medicine, Jen Ai Hospital, Taichung, Taiwan.
Insights
Adult-type idiopathic hypertrophic pyloric stenosis (IHPS) is rare. This case report highlights a 47-year-old male diagnosed with IHPS presenting with gastric outlet obstruction, emphasizing its rarity in adults.
Area of Science:
- Gastroenterology
- Surgical Pathology
Background:
- Idiopathic hypertrophic pyloric stenosis (IHPS) is primarily diagnosed in infants.
- Adult-onset IHPS is an exceptionally rare condition, though documented since the 19th century.
Observation:
- A 47-year-old male presented with postprandial nausea and vomiting.
- Diagnostic workup revealed gastric outlet obstruction due to pyloric stenosis.
- Imaging showed distal stomach wall thickening, raising concern for malignancy.
Findings:
- Surgical pathology confirmed IHPS, characterized by pyloric muscle hypertrophy and hyperplasia.
- Malignancy was definitively excluded.
- The patient underwent antrectomy with Billroth I anastomosis.
Implications:
- This case underscores the importance of considering adult IHPS in the differential diagnosis of gastric outlet obstruction.
- Awareness of this rare condition is crucial for timely diagnosis and appropriate management.
- Further research into adult IHPS pathogenesis and optimal treatment strategies may be warranted.
Abstract:
Idiopathic hypertrophic pyloric stenosis (IHPS) is a predominantly infantile disease. The adult type of IHPS is extremely rare but it has been well recognized since the 19(th) century. We report a case of a 47-year-old male patient who presented with postprandial nausea and vomiting. He underwent upper gastrointestinal endoscopy, and gastric outlet obstruction was discovered. The upper gastrointestinal barium study showed a distended stomach with delayed gastric emptying due to pyloric stenosis. The abdominal computed tomography revealed thickening of the distal stomach. Since gastric malignancy could not be excluded, he underwent antrectomy with Billroth I anastomosis. The pathology revealed no malignancy but showed hypertrophy and hyperplasia of the inner circular muscle of the pylorus, which was compatible with IHPS. We reported the case to remind young physicians of this rare disease.
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