Adult idiopathic hypertrophic pyloric stenosis

Hsien-Ping Lin1, Yu-Chiang Lin2, Chen-Yun Kuo3

  • 1Division of Gastroenterology, Department of Internal Medicine, Jen Ai Hospital, Taichung, Taiwan.

Insights

Adult-type idiopathic hypertrophic pyloric stenosis (IHPS) is rare. This case report highlights a 47-year-old male diagnosed with IHPS presenting with gastric outlet obstruction, emphasizing its rarity in adults.

Area of Science:

  • Gastroenterology
  • Surgical Pathology

Background:

  • Idiopathic hypertrophic pyloric stenosis (IHPS) is primarily diagnosed in infants.
  • Adult-onset IHPS is an exceptionally rare condition, though documented since the 19th century.

Observation:

  • A 47-year-old male presented with postprandial nausea and vomiting.
  • Diagnostic workup revealed gastric outlet obstruction due to pyloric stenosis.
  • Imaging showed distal stomach wall thickening, raising concern for malignancy.

Findings:

  • Surgical pathology confirmed IHPS, characterized by pyloric muscle hypertrophy and hyperplasia.
  • Malignancy was definitively excluded.
  • The patient underwent antrectomy with Billroth I anastomosis.

Implications:

  • This case underscores the importance of considering adult IHPS in the differential diagnosis of gastric outlet obstruction.
  • Awareness of this rare condition is crucial for timely diagnosis and appropriate management.
  • Further research into adult IHPS pathogenesis and optimal treatment strategies may be warranted.

Related Concept Videos

Peptic Ulcer01:27

Peptic Ulcer

Peptic ulcers are erosive lesions of the gastric or duodenal lining, most commonly caused by Helicobacter pylori infection. This Gram-negative, helical bacterium has adapted to survive the stomach’s acidic environment by producing urease, which converts urea into ammonia and carbon dioxide. The ammonia neutralizes gastric acid in the bacterium’s immediate environment, allowing colonization of the gastric mucosa. H. pylori attaches to mucus-secreting epithelial cells, penetrates the...
31
Peptic Ulcer Disease I: Introduction01:30

Peptic Ulcer Disease I: Introduction

Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
1.1K
Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
958
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies01:28

Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies

Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
820
Peptic Ulcer Disease V: Surgical Management and Nursing Care01:25

Peptic Ulcer Disease V: Surgical Management and Nursing Care

Surgical management and nursing care are crucial in treating Peptic Ulcer Disease (PUD). Here is an organized and enhanced overview of the surgical interventions and the associated nursing care for PUD:
Surgical Interventions for Peptic Ulcer Disease
1.2K
Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
1.2K