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Published on: December 6, 2016
Model for prediction of pediatric OSA: Proposal for a clinical decision rule
Victor Certal1,2, Hélder Silva2, Carlos Carvalho2
1Department of Otorhinolarygology/Sleep Medicine Centre-Hospital CUF, Porto.
Insights
A new clinical decision rule effectively predicts obstructive sleep apnea (OSA) in children aged 3-6 years using simple factors like sleep questionnaire scores and tonsil size.
Area of Science:
- Pediatric Sleep Medicine
- Otorhinolaryngology
- Diagnostic Accuracy
Background:
- Obstructive sleep apnea (OSA) is common in children but lacks optimal diagnostic tools.
- Accurate prediction of pediatric OSA is crucial for timely intervention.
Purpose of the Study:
- To develop a clinical decision rule for predicting pediatric OSA in children aged 3-6 years.
- To utilize readily available clinical information for OSA prediction.
Main Methods:
- Prospective cohort study involving 67 children aged 3-6 years with suspected OSA.
- Data collected included age, weight, height, BMI, Pediatric Sleep Questionnaire (PSQ) scores, tonsil size, and oxygen desaturation index (ODI).
- Logistic regression modeling was employed to create a prediction model.
Main Results:
- The final model identified PSQ score, ODI, and tonsil size as significant predictors of pediatric OSA.
- The developed clinical decision rule demonstrated high diagnostic accuracy with 88% sensitivity and 86% specificity.
- The area under the ROC curve was 0.897, indicating strong predictive performance.
Conclusions:
- A clinical decision rule based on PSQ score, ODI, and tonsil size is a promising tool for predicting pediatric OSA.
- This rule offers a valuable method for discriminating OSA risk in young children.
- The findings support the use of this rule in clinical practice for children aged 3-6 years.
Objectives/Hypothesis:
Obstructive sleep apnea (OSA) is a syndrome frequently diagnosed in children; however, it lacks optimal diagnostic methods. This study aimed to provide a clinical decision rule for predicting pediatric OSA using commonly available clinical information.
Study Design:
A prospective cohort study.
Methods:
Children between the ages of 3 to 6 years-old, referred for an otorhinolaryngology consultation due to clinical suspicion of OSA, were recruited from January to June 2014. At baseline age, weight, height, gender, body mass index, Pediatric Sleep Questionnaire (PSQ) scores, tonsil size, and oxygen desaturation index (ODI) were assessed. A logistic regression modeling was used with backward stepwise elimination to develop a prediction model.
Results:
Sixty-seven children were included with a mean age of 4.51 years. Of the 67 children included in this study, 25 (37.3%) subjects were diagnosed with pediatric OSA. Significant predictors of pediatric OSA in the final model (odds ratio, 95% confidence interval) included PSQ score (5.12; 3.3-6.5), ODI (1.34; 1.0-1.79) and tonsil size (6.7; 3.22-9.75). The final decision rule had a sensitivity of 88% and a specificity of 86%. The area under the receiver operating characteristic curve was 0.897.
Conclusion:
The proposed clinical decision rule, based on three readily available variables, is a promising discriminating instrument for prediction of OSA among children between 3 and 6 years.
Level Of Evidence:
2b.
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