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Published on: June 2, 2018
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[Nonfunctioning pancreatic neuroendocrine tumor with extensive calcification]
Sho Sasaki1, Hidekazu Mukai, Atsushi Sugahara
1Department of Gastroenterology, Yodogawa Christian Hospital.
Summary
A rare case of a nonfunctioning pancreatic neuroendocrine tumor (PNET) with extensive calcification was identified in a 54-year-old woman. Surgical removal confirmed the diagnosis, highlighting a unique presentation of PNET.
Area of Science:
- Gastroenterology and Hepatology
- Surgical Oncology
- Endocrinology
Background:
- Pancreatic neuroendocrine tumors (PNETs) are rare neoplasms.
- Calcification within PNETs is an uncommon finding.
- Nonfunctioning PNETs often present at later stages due to lack of hormonal symptoms.
Observation:
- A 54-year-old woman presented with pancreatic calcification on ultrasonography.
- Imaging revealed a 20-mm pancreatic mass with significant calcification.
- The mass showed weak enhancement on contrast-enhanced CT.
Findings:
- Histopathological diagnosis confirmed a nonfunctioning pancreatic neuroendocrine tumor (PNET), grade 2.
- The PNET exhibited extensive calcification, a rare characteristic.
- Surgical resection included pancreatectomy and splenectomy.
Implications:
- This case highlights the importance of considering PNET in patients with pancreatic calcification.
- Extensive calcification may influence diagnostic imaging interpretation of PNETs.
- Further research into the pathogenesis and clinical significance of calcified PNETs is warranted.
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