Related Experiment Video
Updated: Apr 7, 2026

Microsurgical Creation of Giant Bifurcation Aneurysms in Rabbits for the Evaluation of Endovascular Devices
Published on: September 8, 2023
[Ventricular aneurysm as a complication of giant cell myocarditis]
Enrico Ammirati1, Alberto Roghi2, Fabrizio Oliva3
1Cardiologia 2 - Insufficienza Cardiaca e Trapianto.
Insights
Giant cell myocarditis can lead to ventricular aneurysms, a late complication that may cause sudden arrhythmic death. Cardiac MRI and defibrillators can help manage this risk in survivors.
Area of Science:
- Cardiology
- Pathology
Background:
- Giant cell myocarditis is a rare, aggressive inflammatory heart condition.
- Ventricular aneurysms are a known, albeit infrequent, late complication.
Observation:
- This case highlights ventricular aneurysm formation as a late sequela of giant cell myocarditis.
- The aneurysm occurred in a patient who survived the initial life-threatening phase.
Findings:
- Ventricular aneurysm formation presents a risk for sudden arrhythmic death.
- This risk persists even with preserved left ventricular ejection fraction and no recurrent inflammation.
Implications:
- Cardiac magnetic resonance imaging is crucial for detecting small, potentially asymptomatic aneurysms.
- Implantable cardioverter-defibrillators should be considered for patients with this complication to prevent sudden death.
Abstract:
Ventricular aneurysm as late complication has been described in cardiac sarcoidosis and occasionally in giant cell myocarditis. The images from the present case of ventricular aneurysm formation as a late complication of giant cell myocarditis underline a potential cause of sudden arrhythmic death in patients who survive this life-threatening condition in the absence of recurrent inflammation and with preserved left ventricular ejection fraction. Follow-up with cardiac magnetic resonance can detect small aneurysms, and an implantable cardioverter-defibrillator may be considered when this complication occurs.
More Related Videos
Related Concept Videos
Myocarditis I: Introduction
Myocarditis III: Medical Management
Rheumatic Heart Disease I: Introduction
Cardiomyopathy II: Dilated Cardiomyopathy
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Aneurysm III: Interprofessional Care

