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Updated: Apr 7, 2026

Standardized Model of Ventricular Fibrillation and Advanced Cardiac Life Support in Swine
Published on: January 30, 2020
Refractory ventricular fibrillation managed by coronary revascularisation performed during ongoing manual cardiac
Udit Bhaskar Bhatnagar1, Ata Bajwa1, Amit Sharma2
1Department of Internal Medicine, University of Missouri-Kansas City, Kansas City, Missouri, USA.
Insights
Emergent coronary angiography during cardiopulmonary resuscitation successfully treated refractory ventricular fibrillation caused by in-stent thrombosis. This intervention led to the patient's excellent recovery and discharge.
Area of Science:
- Cardiology
- Interventional Cardiology
- Critical Care Medicine
Background:
- Ventricular arrhythmias frequently result from myocardial infarction.
- Percutaneous coronary intervention is rarely employed during active resuscitation for persistent ventricular arrhythmias.
Observation:
- A case of refractory ventricular fibrillation due to in-stent thrombosis during ongoing resuscitation is presented.
- The patient required prolonged cardiopulmonary resuscitation (1.5 hours).
Findings:
- Emergent coronary angiogram and stent placement were performed during active cardiopulmonary resuscitation.
- The intervention successfully managed the in-stent thrombosis and ventricular fibrillation.
Implications:
- Performing percutaneous coronary intervention during resuscitation can be a life-saving strategy for specific cases of myocardial infarction-induced ventricular arrhythmias.
- This case highlights the feasibility and positive outcomes of emergent invasive procedures in critical care settings.
Abstract:
Myocardial infarction is the most common cause of ventricular arrhythmias. Although there have been several improvements and refinements in coronary catheterisation with percutaneous intervention over the years, this intervention is still rarely considered during active ongoing resuscitation of patients, especially in cases of persistent ventricular arrhythmias. We present a case of refractory ventricular fibrillations due to in-stent thrombosis that was managed by emergent coronary angiogram and stent placement during ongoing cardiopulmonary resuscitation in a code that lasted about 1½ h. The patient subsequently made an excellent recovery and was discharged home 13 days later.
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