Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Vision01:24

Vision

61.6K
Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
61.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Neural Dynamics during Binocular Rivalry: Indications from Human Lateral Geniculate Nucleus.

eNeuro·2023
Same author

Assessment of human expertise and movement kinematics in first-person shooter games.

Frontiers in human neuroscience·2022
Same author

From the Group to the Individual in Schizophrenia Spectrum Disorders: Biomarkers of Social Cognitive Impairments and Therapeutic Translation.

Biological psychiatry·2021
Same author

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne·2021
Same author

Problems in the deployment of machine-learned models in health care.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne·2021
Same author

Spatially Specific Working Memory Activity in the Human Superior Colliculus.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2020

Related Experiment Video

Updated: Apr 7, 2026

Topographical Estimation of Visual Population Receptive Fields by fMRI
06:02

Topographical Estimation of Visual Population Receptive Fields by fMRI

Published on: February 3, 2015

9.8K

Population Receptive Field Estimation Reveals New Retinotopic Maps in Human Subcortex.

Kevin DeSimone1, Joseph D Viviano2, Keith A Schneider2

  • 1Department of Psychology, Centre for Vision Research, and desimone@yorku.ca.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|July 10, 2015
PubMed
Summary

Researchers discovered new visual maps in the human subcortex using a novel modeling approach. This advances our understanding of subcortical nuclei like the thalamic reticular nucleus and substantia nigra in visual processing.

Keywords:
lateral geniculate nucleuspopulation receptive fieldpulvinarsubstantia nigrasuperior colliculusthalamic reticular nucleus

More Related Videos

Investigating Object Representations in the Macaque Dorsal Visual Stream Using Single-unit Recordings
07:08

Investigating Object Representations in the Macaque Dorsal Visual Stream Using Single-unit Recordings

Published on: August 1, 2018

8.8K
Author Spotlight: Insights into Visual Cortex Research Through Wide-View fMRI Mapping
07:11

Author Spotlight: Insights into Visual Cortex Research Through Wide-View fMRI Mapping

Published on: December 8, 2023

2.6K

Related Experiment Videos

Last Updated: Apr 7, 2026

Topographical Estimation of Visual Population Receptive Fields by fMRI
06:02

Topographical Estimation of Visual Population Receptive Fields by fMRI

Published on: February 3, 2015

9.8K
Investigating Object Representations in the Macaque Dorsal Visual Stream Using Single-unit Recordings
07:08

Investigating Object Representations in the Macaque Dorsal Visual Stream Using Single-unit Recordings

Published on: August 1, 2018

8.8K
Author Spotlight: Insights into Visual Cortex Research Through Wide-View fMRI Mapping
07:11

Author Spotlight: Insights into Visual Cortex Research Through Wide-View fMRI Mapping

Published on: December 8, 2023

2.6K

Area of Science:

  • Neuroscience
  • Visual Neuroscience
  • Functional Neuroimaging

Background:

  • The human subcortex plays a crucial role in transmitting information to and from cortical areas.
  • Retinotopic maps in subcortical visual nuclei are essential for visual processing but are challenging to measure precisely.
  • Previous methods struggled with accurately mapping these small structures, especially in the eccentricity dimension.

Purpose of the Study:

  • To develop and apply a novel method for precisely measuring retinotopic maps in small subcortical nuclei.
  • To identify and characterize previously unreported retinotopic maps within the human subcortex.
  • To explore the functional organization of visual pathways in subcortical structures.

Main Methods:

  • Utilized the population receptive field (pRF) model to estimate voxel response properties.
  • Applied pRF modeling to functional magnetic resonance imaging (fMRI) data to resolve retinotopic maps.
  • Combined functional data with anatomical MRI (proton density-weighted images) to delineate subcortical nuclei boundaries.

Main Results:

  • Resolved two previously unreported retinotopic maps in the thalamic reticular nucleus and the substantia nigra.
  • Successfully measured polar angle, eccentricity, receptive field size, and hemodynamic response function delay in multiple subcortical nuclei.
  • Confirmed functional activations within anatomically defined boundaries of the studied nuclei.

Conclusions:

  • The population receptive field model enables precise measurement of retinotopic organization in small subcortical nuclei.
  • This study reveals new insights into the visual processing capabilities of the thalamic reticular nucleus and substantia nigra.
  • Mapping subcortical retinotopy is a foundational step toward understanding their roles in neural dynamics and visual perception.