Sufficient and necessary conditions for Lyapunov stability of genetic networks with SUM regulatory logic
Guopeng Zhou1, Jinhua Huang2, Fengxia Tian1
1Institute of Engineering and Technology, Hubei University of Science and Technology, Xianning, 437100 China.
Abstract:
In this paper, a nonlinear model for genetic regulator networks (GRNs) with SUM regulatory logic is presented. Four sufficient and necessary conditions of global asymptotical stability and global exponential stability for the equilibrium point of the GRNs are proposed, respectively. Specifically, three weak sufficient conditions and corresponding corollaries are derived by using comparing theorem and Dini derivative method. Then, a famous GRN model is used as the example to illustrate the effectiveness of our theoretical results. Comparing to the results in the previous literature, some novel ideas, study methods and interesting results are explored.
Related Concept Videos
Operon Model
Constitutive and Regulated Gene Expression
Combinatorial Gene Control
The expression of more than 30,000 genes is controlled by approximately 2000-3000 transcription factors. This is possible because a single transcription factor can recognize more than one regulatory sequence. The specificity in gene...
Covalently Linked Protein Regulators
Covalently Linked Protein Regulators
These groups modify specific amino acids in a protein....
Global Regulatory Systems


