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Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
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The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...
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Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
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Mallory-Weiss Tear in the Duodenum.

Jay S Chouhan1, Yezaz A Ghouri1, Katherine A Jelinek2

  • 1Department of Internal Medicine, University of Texas Health Science Center, Houston, TX.

ACG Case Reports Journal
|July 10, 2015
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Summary

This study reports the first known case of a Mallory-Weiss tear occurring in the duodenum, not the typical gastroesophageal junction. This finding expands understanding of upper gastrointestinal mucosal lacerations after forceful retching.

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Area of Science:

  • Gastroenterology
  • Internal Medicine
  • Clinical Case Reports

Background:

  • Mallory-Weiss tears are common mucosal lacerations.
  • These tears typically occur at the gastroesophageal junction.
  • Duodenal Mallory-Weiss tears have not been previously documented.

Observation:

  • A 57-year-old male patient presented with hematemesis.
  • The hematemesis was preceded by episodes of forceful retching.
  • Endoscopic examination revealed a mucosal tear in the descending duodenum.

Findings:

  • The study presents the first documented case of a Mallory-Weiss tear in the descending duodenum.
  • Pathophysiological mechanisms for duodenal injury are discussed in comparison to typical gastroesophageal tears.
  • The tear was attributed to the forceful retching experienced by the patient.

Implications:

  • This finding expands the known anatomical locations for Mallory-Weiss tears.
  • It suggests that duodenal mucosal integrity can be compromised by similar mechanisms causing gastroesophageal tears.
  • Further research may elucidate the specific factors predisposing the duodenum to such injuries.