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Remission of Refractory Celiac Disease With Infliximab in a Pediatric Patient
Nidhi Rawal1, William Twaddell2, Alessio Fasano3
1Division of Pediatric Gastroenterology, Hepatology and Nutrition, University of Maryland, Baltimore, MD.
Abstract:
Refractory celiac disease (RCD) is a rare but life-threatening complication of celiac disease (CD), and only 1 pediatric case has been reported. We report a case of a 14-year-old girl with CD presenting with persistent symptoms and positive tissue celiac-specific antibodies despite a gluten-free diet. Push enteroscopy showed jejunal scalloping and partial villous atrophy on histology. She was diagnosed with RCD and treated with infliximab with subsequent complete serological and histological remission.
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