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Updated: Apr 7, 2026
12:06
Optic Nerve Transection: A Model of Adult Neuron Apoptosis in the Central Nervous System
Published on: May 12, 2011
21.6K
[Visual impairment due to rare optic nerve tumor]
Summary
Optic nerve sheath meningioma caused vision loss in a patient. Prompt diagnosis via MRI and CT, followed by prednisolone treatment, led to symptom improvement, with ongoing monitoring planned.
Area of Science:
- Ophthalmology
- Neurology
- Radiology
Background:
- Optic nerve sheath meningiomas (ONSMs) are rare tumors that can cause significant visual impairment.
- Early diagnosis and appropriate management are crucial for preserving vision.
Observation:
- A 49-year-old male presented with acute vision reduction and relative afferent pupillary defects.
- Static perimetry revealed severe visual field defects, initially suggesting optic neuritis.
Findings:
- MRI identified an intraocular, semicircular mass encasing the optic nerve.
- CT confirmed partial calcification of the mass, leading to an ONSM diagnosis.
- Visual acuity and visual fields improved with prednisolone therapy.
Implications:
- This case highlights the importance of advanced imaging in diagnosing optic nerve pathologies.
- Conservative management with monitoring may be suitable for some ONSM cases, especially after initial response to steroids.
- Interdisciplinary collaboration is key in managing complex ophthalmic conditions.
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