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Septic Arthritis and Osteomyelitis Caused by Pasteurella multocida
Neil Vranis, Ebrahim Paryavi, Matthew Christian
1R Adams Cowley Shock Trauma Center, Department of Orthopaedics, University of Maryland Medical Center, Baltimore, MD. rpensy@umoa.umm.edu.
American Journal of Orthopedics (Belle Mead, N.J.)
|July 11, 2015
Summary
A rare Pasteurella multocida infection caused severe septic arthritis and osteomyelitis, potentially triggered by corticosteroid use. This case highlights the importance of thorough patient history for diagnosing unusual infections, especially in immunocompromised individuals.
Area of Science:
- Infectious Diseases
- Rheumatology
- Pharmacology
Background:
- Systemic corticosteroid use can predispose individuals to opportunistic infections.
- Pasteurella multocida is a rare cause of severe bone and joint infections.
Observation:
- A patient developed progressive septic arthritis and osteomyelitis due to Pasteurella multocida.
- Symptoms recurred a month after initial antibiotic and surgical treatment, suggesting a complex or persistent infection.
Findings:
- The infection was linked to the patient's use of systemic corticosteroids.
- This specific combination of a rare pathogen and corticosteroid provocation leading to recurrent, life-threatening infection is unprecedented.
Implications:
- Clinicians should consider Pasteurella multocida in cases of severe septic arthritis/osteomyelitis, particularly in patients on corticosteroids.
- Vigilance in patient history, especially regarding immunocompromise and medication use, is crucial for diagnosing challenging infections.
- Early recognition and comprehensive management are vital for improving outcomes in such severe cases.
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