Related Experiment Video
Updated: Apr 7, 2026
07:00
Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
6.4K
Primary Sinonasal Clear Cell Carcinoma: Case Report.
S T Davina1, L Linda2, A Abdul Razak2
1Hospital Melaka, Otorhinolaryngology, Jalan Mufti Haji Khalil, Melaka, Melaka 75400, Malaysia. davinastasia@gmail.com.
The Medical Journal of Malaysia
|July 12, 2015
Summary
This case study presents a rare instance of primary sinonasal clear cell carcinoma, a type of malignant epithelial tumor. The patient underwent successful endoscopic tumor excision with no recurrence observed at 10 months post-surgery.
Area of Science:
- Oncology
- Pathology
Background:
- Primary sinonasal clear cell carcinoma is a rare malignant epithelial tumor.
- It is classified under salivary gland-type carcinomas by the World Health Organization (WHO).
Purpose of the Study:
- To report a rare case of primary sinonasal clear cell carcinoma.
- To highlight diagnostic challenges and differential diagnoses.
Main Methods:
- A case of a 69-year-old gentleman with epistaxis was investigated.
- Nasal endoscopy revealed a tumor in the right ethmoid cells.
- Endoscopic excision and histopathological examination confirmed clear cell carcinoma.
- Clinical, immunohistochemical, and radiological examinations excluded other primary or secondary sites.
Main Results:
- Histopathology confirmed primary sinonasal clear cell carcinoma.
- The patient remained well with no tumor recurrence 10 months post-operation.
Conclusions:
- Primary sinonasal clear cell carcinoma is a rare entity.
- Meticulous microscopic examination and special immunostains are crucial for differential diagnosis.
