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GEP-NETs UPDATE: Secreting gastro-enteropancreatic neuroendocrine tumours and biomarkers
Wieke H M Verbeek1, Catharina M Korse1, Margot E T Tesselaar2
1Departments of GastroenterologyClinical ChemistryMedical OncologyThe Netherlands Cancer Institute - Antoni van Leeuwenhoek, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.
Abstract:
Neuroendocrine tumours (NETs) are rare tumours with an annual incidence in the population in a range of 2-5 new cases per 100,000 inhabitants. NETs are widely variable in terms of anatomical location, hormone production, clinical behaviour and syndromes they can cause. This article reviews the many localizations and clinical presentations of NETs with a main focus on clinical biomarkers and their use in medical practice.
