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Online Transcranial Magnetic Stimulation Protocol for Measuring Cortical Physiology Associated with Response Inhibition

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Linking trait-based phenotypes to prefrontal cortex activation during inhibitory control.

Achala H Rodrigo¹, Stefano I Di Domenico¹, Bryanna Graves¹

¹Department of Psychology, University of Toronto Scarborough, Toronto, Ontario, Canada and.

Social Cognitive and Affective Neuroscience

|July 12, 2015

Summary

Personality traits like extraversion and conscientiousness are linked to brain activity in the prefrontal cortex during inhibitory control tasks. Higher levels of these traits correlate with increased prefrontal cortex activation.

Keywords:

five-factor model inhibitory control personality traits prefrontal cortex

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Area of Science:

Neuroscience
Cognitive Psychology
Personality Psychology

Background:

Inhibitory control relies on prefrontal cortex (PFC) function.
Personality traits may influence PFC activity during cognitive tasks.

Purpose of the Study:

To investigate the relationship between normal-range personality traits and PFC activation during inhibitory control.
To examine how trait-based phenotypes modulate neural activity in lateral and medial PFC.

Main Methods:

106 adults completed a manual go/no-go task.
Continuous-wave functional near-infrared spectroscopy (fNIRS) measured hemodynamic oxygenation in the PFC.
Personality traits were assessed using a unified model.

Main Results:

Higher extraversion, agreeableness, and conscientiousness correlated with greater lateral PFC activation.
Lower neuroticism was associated with increased lateral PFC activation.
Higher agreeableness was linked to greater medial PFC activation during inhibitory control.

Conclusions:

Personality traits associated with emotional stability and prosocial behavior may enhance PFC recruitment for inhibitory control.
Findings suggest a neural basis for how personality influences cognitive control processes.
Links between trait phenotypes and PFC activation patterns in inhibitory control are highlighted.