Related Experiment Video
Updated: Apr 7, 2026

Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments
Published on: April 24, 2020
Intraocular Pressure During Robotic-assisted Laparoscopic Procedures Utilizing Steep Trendelenburg Positioning
Todd J Mondzelewski1, Joseph W Schmitz, Matthew S Christman
1Departments of †Urology *Ophthalmology §Anesthesiology, Naval Medical Center San Diego, San Diego, CA ‡Department of Ophthalmology, Naval Medical Center Portsmouth, VA.
Steep Trendelenburg positioning during robotic-assisted laparoscopy significantly elevates intraocular pressure in patients with healthy eyes. Further research is recommended for patients with pre-existing ocular conditions.
Area of Science:
- Ophthalmology
- Surgical Technology
- Anesthesiology
Background:
- Robotic-assisted laparoscopy (RAL) often requires steep Trendelenburg (sTBURG) positioning.
- The impact of sTBURG on intraocular pressure (IOP) in patients without ocular disease is not fully understood.
- Elevated IOP can pose risks to ocular health.
Purpose of the Study:
- To investigate the effect of sTBURG positioning during RAL on IOP.
- To compare IOP changes in patients undergoing RAL with sTBURG versus traditional surgical positions.
- To assess potential ocular risks associated with sTBURG in patients with healthy eyes.
Main Methods:
- Prospective cohort study comparing 18 patients in RAL with sTBURG to 21 controls in horizontal open or laparoscopic surgery.
- Ophthalmologic examinations preoperatively and 1 month postoperatively, including visual acuity, IOP, visual fields, and OCT.
- Intraoperative IOP measurements at discrete time-points.
Main Results:
- Baseline IOP was similar across all groups.
- A significant IOP plateau of 29.9 mm Hg was observed during RAL with sTBURG.
- No significant changes in OCT RNFL thickness or visual field parameters were detected.
Conclusions:
- Robotic surgery utilizing sTBURG positioning leads to significant IOP elevations in patients with healthy eyes.
- A multidisciplinary approach is recommended to evaluate risks for patients with known ocular disease undergoing these procedures.
- Further investigation into long-term ocular effects and risk mitigation strategies is warranted.
Related Concept Videos
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment
Glaucoma: Overview

