Related Experiment Video
Updated: Apr 7, 2026

Author Spotlight: Integrating 2D-HPLC-MS and Molecular Networking in Natural Medicine Analysis
Published on: December 8, 2023
A new anti-inflammatory β-carboline alkaloid from the hairy-root cultures of Eurycoma longifolia
Pham Bich Ngoc1, Thanh Binh Pham2, Hai Dang Nguyen2
1a Institute of Biotechnology , Vietnam Academy of Science and Technology , 18-Hoang Quoc Viet, Cau Giay, Hanoi , Vietnam.
Abstract:
One new β-carboline alkaloid 7-methoxy-(9H-β-carbolin-1-il)-(E)-1-propenoic acid (1) together with 9-methoxycanthin-6-one (2) and 9-hydroxycanthin-6-one (3) were isolated from the hairy-root cultures of Eurycoma longifolia. The effects of these compounds on lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW264.7 cells were investigated. Compound 1 strongly inhibited the production of NO while 2 and 3 having weak or inactive effect. Consistently, compound 1 decreased the expression of cyclooxygenase-2 and inducible nitric oxide synthase.
More Related Videos
07:16Preparation of Gynura bicolor DC samples for High-Resolution Tandem Mass Spectrometry
Published on: February 2, 2024
07:36Analysis of Raw and Processed Cyperi Rhizoma Samples Using Liquid Chromatography-Tandem Mass Spectrometry in Rats with Primary Dysmenorrhea
Published on: December 23, 2022
Related Concept Videos
Drugs that Stabilize Microtubules
Adrenergic Antagonists: ɑ and β-Receptor Blockers
Drugs Acting on Autonomic Ganglia: Blockers
Antihypertensive Drugs: Types of β-Blockers
Antihypertensive Drugs: Action of β1 Blockers
Adrenergic Antagonists: Pharmacological Actions of β-Receptor Blockers