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Published on: March 29, 2022
New cytotoxic constituents from the Red Sea soft coral Nephthea sp
Mohamed-Elamir F Hegazy1, Amira M Gamal-Eldeen2, Tarik A Mohamed1
1a Phytochemistry Department and Center of Excellence for Advanced Sciences, National Research Centre , 33 El Bohouth st. (Former El Tahrir st.) Dokki, Giza, P.O. Box 12622, Egypt.
Abstract:
Nephthea are soft coral species rich in sesquiterpenoids and steroids. An organic extract of Nephthea sp. resulted in the isolation of a new steroid (1), as well as several previously reported metabolites (2-9). Structures were elucidated by employing NMR and HR-EI-MS analyses. The total extract, fractions and purified compounds exhibited differential cytotoxicity against the breast cancer MCF-7 cell line.
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